In contemporary psychiatry and mental health care, techniques grounded in Indian contemplative traditions, such as meditation and breathing practices, are not only actively employed in clinical settings but have also become deeply integrated into everyday life through smartphone applications related to psychotherapy. However, efforts to accurately interpret and systematically examine the psychotherapeutic traditions preserved in classical Indian texts, as well as attempts to scientifically verify the clinical effects of these practices, remain insufficiently developed. In this context, the University of Nebraska Medical Center and the Center for South Asian Studies, Seoul National University seek to undertake a joint research project that reinterprets the historical development and theoretical foundations of Indian psychotherapeutic traditions through textual analysis, while empirically examining the neuroscientific effects of these techniques using fMRI. This roundtable will provide an opportunity to discuss the scope and direction of this prospective collaborative research.